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   BC043071;BC043071
Protein Sequence Comparative Analysis   (PSCA)
 
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BC043071    REFERENCE SYSTEM

Accession: BC043071
Description: BC043071 Mus musculus U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2, mRNA (cDNA clone MGC:57976 IMAGE:6403830), complete cds, coding region:146-1561
Organism: MUS MUSCULUS
Keyword: BC043071 Mus musculus U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2, mRNA (cDNA clone MGC:57976 IMAGE:6403830), complete cds, coding region:146-1561

  

References           
PMID Filter
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     Reference classification      Trusted or extreme similarity       Gathering or high similarity       Noise or low similarity
 
Sequence reference                    
   SP-EMBL: ;  PMID:;
   GenBank: ;  PMID:;
Family annotation                  
1.          trusted          evalue:1.9e-31
    Pfam:v3_1_0:1o0pA00   0;  PMID:;
2.          trusted          evalue:4.4e-29
    Pfam:v3_1_0:1hl6C00   0;  PMID:;
3.          trusted          evalue:1.2e-21
    Pfam:PF00076   RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain);  PMID:8290338;
4.          trusted          evalue:1.5e-20
    Pfam:v3_1_0:2hzcA00   0;  PMID:;
5.          trusted          evalue:3.2e-19
    Pfam:v3_1_0:2u2fA00   0;  PMID:;
6.          trusted          evalue:5.6e-19
    Pfam:v3_1_0:1sxl000   0;  PMID:;
7.          trusted          evalue:1.8e-17
    Pfam:v3_1_0:1p1tA00   0;  PMID:;
8.          trusted          evalue:2.0e-19
    Pfam:v3_1_0:1rk8A00   0;  PMID:;
9.          trusted          evalue:2.1e-18
    Pfam:v3_1_0:1l3kA02   0;  PMID:;
10.          trusted          evalue:1.4e-17
    Pfam:v3_1_0:1x5uA01   0;  PMID:;
11.          trusted          evalue:2.3e-19
    Pfam:v3_1_0:1h2vZ00   0;  PMID:;
12.          trusted          evalue:1.2e-17
    Pfam:v3_1_0:1n54B00   0;  PMID:;
13.          trusted          evalue:6.1e-17
    Pfam:v3_1_0:1cvjA01   0;  PMID:;
14.          trusted          evalue:1.4e-16
    Pfam:v3_1_0:1fxlA02   0;  PMID:;
15.          trusted          evalue:9.8e-17
    Pfam:v3_1_0:1l3kA01   0;  PMID:;
16.          trusted          evalue:6.1e-16
    Pfam:v3_1_0:1cvjG02   0;  PMID:;
17.          trusted          evalue:4.4e-17
    Pfam:v3_1_0:1no8A00   0;  PMID:;
18.          trusted          evalue:2.5e-16
    Pfam:v3_1_0:1fjeB01   0;  PMID:;
19.          trusted          evalue:3.4e-15
    Pfam:v3_1_0:1s79A00   0;  PMID:;
20.          trusted          evalue:1.6e-16
    Pfam:v3_1_0:1jmtA00   0;  PMID:;
21.          trusted          evalue:3.1e-15
    Pfam:v3_1_0:1fxlA01   0;  PMID:;
22.          trusted          evalue:1.1e-14
    Pfam:v3_1_0:1oiaB00   0;  PMID:;
23.          trusted          evalue:1.5e-15
    Pfam:v3_1_0:1nu4A00   0;  PMID:;
24.          trusted          evalue:2.6e-14
    Pfam:v3_1_0:2u1a000   0;  PMID:;
25.          trusted          evalue:3.1e-15
    Pfam:v3_1_0:1qm9A01   0;  PMID:;
26.          trusted          evalue:5.9e-14
    Pfam:v3_1_0:1fjeB02   0;  PMID:;
27.          trusted          evalue:3.0e-11
    Pfam:v3_1_0:1sjrA00   0;  PMID:;
28.          trusted          evalue:1.1e-11
    Pfam:v3_1_0:1qm9A02   0;  PMID:;
29.          trusted          evalue:7.2e-10
    Pfam:v3_1_0:3sxlA02   0;  PMID:;
30.          trusted          evalue:1.6e-08
    Pfam:v3_1_0:1cvjH02   0;  PMID:;
31.          trusted          evalue:6.2e-09
    Pfam:v3_1_0:1whvA00   0;  PMID:;
32.          noise          evalue:9.3e-03
    Pfam:PF08648   Protein of unknown function (DUF1777);  PMID:;
 
PDB similairty                    
No.    Start    End    Identity%    Coverage%    Evalue
1.          148          342          100          41.19          1.0e-111
     Pdb:2YH1 MODEL OF HUMAN U2AF65 TANDEM RRM1 AND RRM2 DOMAINS WITH EIGH; PMID:;
     Pdb:2YH0 SOLUTION STRUCTURE OF THE CLOSED CONFORMATION OF HUMAN U2AF6; PMID:;
2.          148          336          89          39.92          3.0e-92
     Pdb:2G4B STRUCTURE OF U2AF65 VARIANT WITH POLYURIDINE TRACT ; PMID:16818232;
3.          148          336          89          39.92          5.0e-92
     Pdb:3VAJ STRUCTURE OF U2AF65 VARIANT WITH BRU5C6 DNA ; PMID:;
     Pdb:3VAL STRUCTURE OF U2AF65 VARIANT WITH BRU5C1 DNA ; PMID:;
     Pdb:4TU9 STRUCTURE OF U2AF65 VARIANT WITH BRU5G6 DNA ; PMID:;
     Pdb:3VAM STRUCTURE OF U2AF65 VARIANT WITH BRU5C2 DNA ; PMID:;
     Pdb:3VAF STRUCTURE OF U2AF65 VARIANT WITH BRU3 DNA ; PMID:;
     Pdb:4TU8 STRUCTURE OF U2AF65 VARIANT WITH BRU5A6 DNA ; PMID:;
     Pdb:3VAG STRUCTURE OF U2AF65 VARIANT WITH BRU3C2 DNA ; PMID:;
     Pdb:3VAH STRUCTURE OF U2AF65 VARIANT WITH BRU3C4 DNA ; PMID:;
     Pdb:3VAI STRUCTURE OF U2AF65 VARIANT WITH BRU3C5 DNA ; PMID:;
     Pdb:3VAK STRUCTURE OF U2AF65 VARIANT WITH BRU5 DNA ; PMID:;
4.          148          336          88          39.92          4.0e-91
     Pdb:4TU7 STRUCTURE OF U2AF65 D231V VARIANT WITH BRU5 DNA ; PMID:;
5.          367          471          100          22.08          6.0e-58
     Pdb:3V4M CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF A U2 SMALL NUCL; PMID:;
     Pdb:2M52 NMR STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) OF U2; PMID:;
     Pdb:4Z2X CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF A U2 SMALL NUCL; PMID:;
6.          368          471          100          21.87          2.0e-57
     Pdb:2M0G STRUCTURE, PHOSPHORYLATION AND U2AF65 BINDING OF THE NTERMIN; PMID:;
     Pdb:1OPI SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) ; PMID:;
     Pdb:1O0P SOLUTION STRUCTURE OF THE THIRD RNA RECOGNITION MOTIF (RRM) ; PMID:12718882;
7.          371          471          100          21.23          6.0e-55
     Pdb:4FXW STRUCTURE OF PHOSPHORYLATED SF1 COMPLEX WITH U2AF65-UHM DOMA; PMID:;
8.          148          237          100          18.90          5.0e-47
     Pdb:1U2F SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN OF HU2AF6; PMID:10449418;
9.          258          342          100          17.83          6.0e-44
     Pdb:2U2F SOLUTION STRUCTURE OF THE SECOND RNA-BINDING DOMAIN OF HU2AF; PMID:10449418;
10.          148          229          100          17.20          2.0e-41
     Pdb:2HZC CRYSTAL STRUCTURE OF THE N-TERMINAL RRM OF THE U2AF LARGE SU; PMID:;
11.          141          335          24          41.19          1.0e-10
     Pdb:2QFJ CRYSTAL STRUCTURE OF FIRST TWO RRM DOMAINS OF FIR BOUND TO S; PMID:;
12.          150          335          24          39.28          1.0e-10
     Pdb:2KXH SOLUTION STRUCTURE OF THE FIRST TWO RRM DOMAINS OF FIR IN TH; PMID:;
     Pdb:2KXF SOLUTION STRUCTURE OF THE FIRST TWO RRM DOMAINS OF FBP-INTER; PMID:;
13.          150          335          24          39.28          1.0e-10
     Pdb:3UWT CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF POLY-U BINDING ; PMID:;
14.          85          112          100          5.73          3.0e-09
     Pdb:1JMT X-RAY STRUCTURE OF A CORE U2AF65/U2AF35 HETERODIMER ; PMID:11551507;
15.          85          112          100          5.73          3.0e-09
     Pdb:4RU2 CRYSTAL STRUCTURE OF A RNA-BINDING PROTEIN 39 (RBM39) IN COM; PMID:;
     Pdb:5CXT CRYSTAL STRUCTURE OF A RNA-BINDING PROTEIN 39 (RBM39) IN COM; PMID:;
16.          253          336          35          17.62          1.0e-08
     Pdb:1P1T NMR STRUCTURE OF THE N-TERMINAL RRM DOMAIN OF CLEAVAGE STIMU; PMID:12773396;
17.          256          335          40          16.77          7.0e-08
     Pdb:1FNX SOLUTION STRUCTURE OF THE HUC RBD1-RBD2 COMPLEXED WITH THE A; PMID:;
18.          256          335          40          16.77          8.0e-08
     Pdb:1D8Z SOLUTION STRUCTURE OF THE FIRST RNA-BINDING DOMAIN (RBD1) OF; PMID:10734193;
19.          255          338          33          17.62          2.0e-07
     Pdb:1U6F NMR SOLUTION STRUCTURE OF TCUBP1, A SINGLE RBD-UNIT FROM TRY; PMID:;
20.          355          470          33          24.42          2.0e-07
     Pdb:3DXB STRUCTURE OF THE UHM DOMAIN OF PUF60 FUSED TO THIOREDOXIN ; PMID:;
21.          360          470          35          23.35          7.0e-07
     Pdb:3UE2 CRYSTAL STRUCTURE OF A RNA BINDING DOMAIN OF POLY-U BINDING ; PMID:;
     Pdb:3US5 CRYSTAL STRUCTURE OF A RNA-BINDING DOMAIN OF A POLY-U BINDIN; PMID:;
22.          371          470          37          21.02          9.0e-07
     Pdb:2DNY SOLUTION STRUCTURE OF THE THIRD RNA BINDING DOMAIN OF FBP- I; PMID:;
23.          261          330          35          14.65          2.0e-06
     Pdb:2X1A STRUCTURE OF RNA15 RRM WITH RNA BOUND (G) ; PMID:;
     Pdb:2X1B STRUCTURE OF RNA15 RRM ; PMID:;
24.          261          330          35          14.65          2.0e-06
     Pdb:2X1F STRUCTURE OF RNA15 RRM WITH BOUND RNA (GU) ; PMID:;
25.          261          330          35          14.65          3.0e-06
     Pdb:2KM8 INTERDOMAIN RRM PACKING CONTRIBUTES TO RNA RECOGNITION IN TH; PMID:;
26.          257          449          26          40.76          6.0e-06
     Pdb:1G2E CRYSTAL STRUCTURE OF HUD AND AU-RICH ELEMENT OF THE TUMOR NE; PMID:11175903;
     Pdb:1FXL CRYSTAL STRUCTURE OF HUD AND AU-RICH ELEMENT OF THE C-FOS RN; PMID:11175903;
27.          261          335          33          15.71          9.0e-06
     Pdb:4EGL CRYSTAL STRUCTURE OF TWO TANDEM RNA RECOGNITION MOTIFS OF HU; PMID:;
     Pdb:4ED5 CRYSTAL STRUCTURE OF THE TWO N-TERMINAL RRM DOMAINS OF HUR C; PMID:;
28.          366          470          37          22.08          1.0e-05
     Pdb:2PE8 CRYSTAL STRUCTURE OF THE UHM DOMAIN OF HUMAN SPF45 (FREE FOR; PMID:;
     Pdb:2PEH CRYSTAL STRUCTURE OF THE UHM DOMAIN OF HUMAN SPF45 IN COMPLE; PMID:;
29.          147          342          21          41.40          1.0e-05
     Pdb:1U1O CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTAG(DI)G); ; PMID:15342234;
     Pdb:1U1P CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTA 2PR GG);; PMID:15342234;
     Pdb:1U1L CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTT PRN GGG);; PMID:15342234;
     Pdb:1L3K UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 ; PMID:11917013;
     Pdb:1U1K CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTT 7DA GGG);; PMID:15342234;
     Pdb:1U1N CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTA (PRN) GG; PMID:15342234;
     Pdb:1U1M CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTA 7GU GG);; PMID:15342234;
     Pdb:1U1Q CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTA(DI)GG); ; PMID:15342234;
     Pdb:1U1R CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTAG(2PR) G); PMID:15342234;
30.          147          342          21          41.40          1.0e-05
     Pdb:1PGZ CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TTAGGGTTAG(6-MI) G; PMID:12904298;
31.          261          335          33          15.71          2.0e-05
     Pdb:4FXV CRYSTAL STRUCTURE OF AN ELAV-LIKE PROTEIN 1 (ELAVL1) FROM HO; PMID:;
32.          147          342          21          41.40          2.0e-05
     Pdb:2LYV SOLUTION STRUCTURE OF THE TWO RRM DOMAINS OF HNRNP A1 (UP1) ; PMID:;
33.          261          335          33          15.71          3.0e-05
     Pdb:3HI9 THE X-RAY CRYSTAL STRUCTURE OF THE FIRST RNA RECOGNITION MOT; PMID:;
34.          147          317          22          36.09          3.0e-05
     Pdb:1HA1 HNRNP A1 (RBD1,2) FROM HOMO SAPIENS ; PMID:8130198;
35.          147          317          22          36.09          3.0e-05
     Pdb:1UP1 UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 ; PMID:9115444;
36.          147          317          22          36.09          3.0e-05
     Pdb:1PO6 CRYSTAL STRUCTURE OF UP1 COMPLEXED WITH D(TAGG(6MI)TTAGGG): ; PMID:12904298;
     Pdb:2UP1 STRUCTURE OF UP1-TELOMERIC DNA COMPLEX ; PMID:10323862;
37.          151          334          23          38.85          4.0e-05
     Pdb:1CVJ X-RAY CRYSTAL STRUCTURE OF THE POLY(A)-BINDING PROTEIN IN CO; PMID:10499800;
38.          151          334          23          38.85          4.0e-05
     Pdb:4F02 CRYSTAL STRUCTURE OF THE PABP-BINDING SITE OF EIF4G IN COMPL; PMID:;
39.          260          332          31          15.29          7.0e-05
     Pdb:2JRS SOLUTION NMR STRUCTURE OF CAPER RRM2 DOMAIN. NORTHEAST STRUC; PMID:;
40.          261          375          31          24.20          9.0e-05
     Pdb:3SMZ HUMAN RAVER1 RRM1-3 DOMAINS (RESIDUES 39-320) ; PMID:;
41.          261          375          31          24.20          1.0e-04
     Pdb:3H2U HUMAN RAVER1 RRM1, RRM2, AND RRM3 DOMAINS IN COMPLEX WITH HU; PMID:;
42.          261          375          31          24.20          1.0e-04
     Pdb:3VF0 RAVER1 IN COMPLEX WITH METAVINCULIN L954 DELETION MUTANT ; PMID:;
43.          257          341          30          17.83          1.0e-04
     Pdb:1B7F SXL-LETHAL PROTEIN/RNA COMPLEX ; PMID:10217141;
44.          257          341          30          17.83          1.0e-04
     Pdb:3SXL SEX-LETHAL RNA RECOGNITION DOMAINS 1 AND 2 FROM DROSOPHILA M; PMID:10220389;
45.          261          332          33          15.07          2.0e-04
     Pdb:2DNZ SOLUTION STRUCTURE OF THE SECOND RNA BINDING DOMAIN OF RNA B; PMID:;
46.          257          341          30          17.83          2.0e-04
     Pdb:2SXL SEX-LETHAL RBD1, NMR, MINIMIZED AVERAGE STRUCTURE ; PMID:9299339,8130198,7984237,7524663,2147232,1385725;
47.          257          341          30          17.83          2.0e-04
     Pdb:4QQB STRUCTURAL BASIS FOR THE ASSEMBLY OF THE SXL-UNR TRANSLATION; PMID:;
48.          149          336          22          39.70          2.0e-04
     Pdb:3MD3 CRYSTAL STRUCTURE OF THE FIRST TWO RRM DOMAINS OF YEAST POLY; PMID:;
49.          259          335          29          16.14          4.0e-04
     Pdb:4C7Q SOLUTION STRUCTURE OF THE NT. GR-RBP1 RRM DOMAIN ; PMID:;
 
NR homologs                 
No.    Start    End    Identity%    Coverage%    Evalue
 

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